What Parents Should Know About the COVID Vaccine for Kids for Under 5

On June 18, the Centers for Disease Control and Prevention (CDC) approved COVID-19 vaccination for young children who are at least 6 months old. This means roughly 20 million children in the United States under 5 years old are newly eligible for vaccination.
With COVID cases remaining high, many parents are eager to vaccinate their youngest kids, and vaccine appointments are expected to start becoming available this week in the Bay Area.
Dr. Grace Lee, Stanford Children’s Health pediatric infectious diseases physician and chair of the U.S. Advisory Committee on Immunization Practices, answers frequently asked questions about vaccines for young children.
“Vaccines continue to be effective at preventing severe illness and hospitalization, including in children without any underlying medical conditions,” says Lee. “Vaccines can protect children, which in turn can reduce the risk of transmission to others. I encourage everyone to keep doing their part to protect themselves and others.”
Why should my baby or young child receive the COVID-19 vaccine?
Since the beginning of the COVID-19 pandemic, there have been over 2 million cases, 20,000 hospitalizations and 200 deaths due to COVID-19 in children under 5 years of age. The CDC recommends a COVID-19 vaccine for children ages 6 months and older.
Scientific evidence has shown that the children who received COVID-19 vaccines during testing developed high levels of virus-fighting antibodies expected to protect them against coronavirus. Vaccines continue to be effective at preventing severe illness and hospitalization, including children with and without any underlying medical conditions.
COVID-19 vaccines can also prevent multisystem inflammatory syndrome in children (MIS-C) and may potentially prevent post-acute sequelae of COVID-19 (PASC) – also known as long COVID – which can be very debilitating for young children. Vaccines can protect children, which in turn can reduce the risk of transmission to others.
What makes this vaccine different from the others administered to kids 5 years and older?
The only COVID-19 vaccine presently available for children older than 5 years in the U.S. is the Pfizer BioNTech mRNA vaccine. For children under 5, we now have two vaccines available. The three-dose Pfizer COVID-19 vaccine can be given to children 6 months to 4 years of age at a 3 microgram dosage. The two-dose Moderna COVID-19 vaccine is recommended for children ages 6 months to 5 years at a dose of 25 micrograms. These doses were carefully selected to ensure the vaccine was well tolerated for young children.
How many doses of vaccine are needed, and on what schedule? 
If your child receives the Pfizer vaccine, it is a three-dose vaccine series: Dose 1, then 3-8 weeks later Dose 2, then more than 8 weeks later Dose 3.
For the Moderna vaccine, it is a two-dose vaccine series: Dose 1, then 4-8 weeks later Dose 2.
Children who are moderately or severely immunocompromised may need additional doses, similar to teens and adults.
How long does it take for the shots to take full effect? 
A child can be considered fully immunized two weeks after the third dose of the Pfizer mRNA vaccine or two weeks after the second dose of the Moderna vaccine. Children who are moderately or severely immunocompromised are considered fully vaccinated two weeks after the final dose in the primary series.
What side effects can parents expect from the vaccines?
The most common side effects parents can expect for their child are a sore arm, headache, fever and fatigue. Children 6–23 months may be fussy or more sleepy. Symptoms usually occur one to two days after vaccination, are mostly mild and resolve after a few days. Parents should contact their primary care provider if they have any specific concerns about side effects from a shot.
My child is immunocompromised. Can he or she get the vaccine?
Yes, children who are immunocompromised should receive vaccines to reduce the risk of severe COVID-19 illness or death. Additional doses are given to children who are moderately or severely immunocompromised, since their immune response to vaccines may not be as strong as in healthy people. Please ask your doctor about when to receive COVID-19 vaccines.
Where should young children be vaccinated?
Going to your child’s primary care provider is recommended for this age group. We encourage you to use all available local and state resources (myturn.ca.gov) to get the COVID-19 vaccine at a place and time that is convenient for your family.
For children who have already gotten COVID-19, is it still worth their getting the vaccine, even if they were already exposed to the most recent variant?
Yes, it is still worthwhile for these children to be vaccinated. While there is protection from natural immunity, it is hard to tell just how durable and protective it is, over time – it varies by the individual. The primary vaccine series offers additional and reliable protection against severe illness and/or death.
How long after my child’s COVID-19 infection should I wait before getting him vaccinated?
The situation may vary depending on a child’s medical history and the severity of the COVID-19 infection, but waiting until all symptoms have resolved is best.
In addition, people who recently had SARS-CoV-2 infection may consider delaying a primary series dose or their first or second COVID-19 vaccine booster dose by three months from symptom onset or positive test (if infection was asymptomatic). Studies have shown that increased time between infection and vaccination may result in an improved immune response to vaccination. Check with your child’s pediatrician for more information.
What can parents do to reduce their child’s risk of getting COVID-19?
About 59% of 12- to 17-year-olds and around 29% of children ages 5–11 are fully vaccinated, according to CDC data. A child is considered up-to-date if they have received all recommended doses for his or her age. Encourage your children and those around you to keep doing their part to protect others by wearing a face mask, doing proper handwashing and following other steps to keep people with a high risk of infection safe.


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